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"Unlike traditional memory designs where signals are often distorted by electromagnetic signals from other components" - every motherboard designer accounts for noise from nieghboring components.
"Killer DoubleShot-X3 Pro allows the two Killer Ethernet connectors and Wi-Fi adapter to work in tandem for the highest speeds around (up to 2.867 Gbps) whether you’re using a wired or wireless connection." - maybe, but you're limited to the slowest point between you and the other computer. Usually Ethernet works in multiples of 10. 1Gbps is common on motherboards, 10Gbps is available for servers or higher-end network cards. Your modem/router may be slower than 1Gbps. Your internet provider, if you live in the US, is either orders of magnitude slower than 1Gbps, unless you paid for business internet access, got Fiber, and/or have had better luck than I have.
"The Killer Network Manager allows users to customize which applications receive the most bandwidth, so you can prioritize your favorite games over other programs." - I wouldn't pay for this. If you want it as a feature, you can get free programs to do this for you. On the other hand, I am a power user and am not afraid of using the terminal/command prompt, and am therefore biased against what is most likely a more user friendly way of managing the speed of network access for your applications.
"Every audio component—from the jacks to the capacitors to the amplifiers—has been engineered to deliver the highest quality sound to satisfy even the most discerning listeners. With Audio Boost 3 Pro, which is powered by Nahimic Sound Technology, it delivers crystal clear 8-channel HD audio to help you hear more detail in your favorite games, movies, and music." - this uses the same 8-channel audio chip and components as almost any other motherboard. I got an AMD motherboard several years ago with 8-channel audio, same SNR ratio, no improvements since then, and that motherboard was less than $200.
"And as opposed to most motherboards, this one is able to deliver a steady stream of 5V power to each USB port" - this is a requirement for any USB port. Literally anything that provides power to USB devices (USB 2.0 or later) does this. Perhaps this has less noise on the 5V power, but it's not enough to affect any properly designed USB device.
"World’s First Built-In Overclocking Motherboard" - yeah...no. I can't remember all of them, but I recall ASUS ROG motherboards having this years ago, and I'm almost certain they weren't the first either.
"When you’re transferring files, use one of the two MSI USB 3.1 Gen 2 ports, which offer transfer speeds up to an impressive 10 Gb/s" - USB 3.1 supports 10Gb/s - this is not specific to MSI.
"the MSI Super Charger is great for quickly charging external devices like smartphones and tablets" - if you own a modern smartphone or tablet, you should be aware by now that MSI isn't the only company with this feature. Also note that most quick-charge systems don't allow data transfer and charging at the same time. You may need to "safely remove hardware" and/or tell your phone that the USB connection is for charge-only. An exception is USB type C, which is available for this motherboard. USB type C is still recent, and will be more common once there are chips readily available to better handle the features it provides.
And, to be fair, some positives:
8 RAM slots instead of the standard 4, allowing 128GB of RAM
plenty of PCI-E and SATA III ports
M.2 slot for SSDs (which is designed to optimize SSD performance, thus allowing faster speeds than SATA - in other words, put your boot drive here)
two 1000 Mb/s ethernet ports (1Gbps each) - normally I've only seen one per motherboard
USB type C port - this is potentially the one connector to rule them all.
Pretty lights - this is where a fair amount of money is going. You can probably find a similar motherboard without the lights at a lower price. But you've got to admit, the lights look cool. Not worth having if you don't have some sort of window on your case, as no one will ever see it.